Goals ›

Joint pain

Joint pain and stiffness in daily life, which studies measure on scales such as WOMAC and the visual analogue scale.

Strongest evidence: Hyaluronic acid, Collagen and Chondroitin.

Supplements for joint pain

Each supplement gets the grade of its strongest joint pain benefit. Open one to see each benefit.

StrongModerateWeakNo trials
SupplementMain effects in studiesEvidenceBenefits studied
Hyaluronic acidPain↓ Function↑, Pain↓ Function↑Strong1 of 1
CollagenPain/function improved, Cartilage breakdown markers ↓Strong1 of 1
ChondroitinPain/function ↓, Cartilage loss ↓Strong1 of 1
GlucosaminePain/function relief −76%, Joint-space loss −0.25 mmStrong1 of 1
Omega-3 fatty acidsLess pain, stiffness, Lower inflammation markersStrong1 of 1
Fish oilJoint pain/stiffness ↓, DAS28/NSAID ↓Strong1 of 1
Type-II CollagenPain ↓, function ↑, CTX-II ↓ or ↑Strong1 of 1
CurcuminPain/function ↓, Inflammation markers ↓Strong1 of 1
TurmericPain ↓, function ↑, +29.2–41.8 mStrong1 of 1
BoswelliaPain/function improve, Inflammation biomarkers dropStrong1 of 1
Showing 10 of 78 supplements.

What joint pain covers

One benefit that studies measure, and the supplements with the strongest evidence for each.

Joint comfort

Joint pain and stiffness in daily life. It is measured on scales such as WOMAC and the visual analogue scale, and it is scored separately from how far a joint can move.

78 supplements, 12 strong
  1. Hyaluronic acidStrong, 299
  2. CollagenStrong, 61
  3. ChondroitinStrong, 58
  4. GlucosamineStrong, 57
  5. Omega-3 fatty acidsStrong, 36