Goals ›

Stress & anxiety

Feeling stressed or anxious, which studies measure with anxiety scales and with cortisol in blood or saliva.

Strongest evidence: GABA, Lavender and Melatonin.

Supplements for stress & anxiety

Each supplement gets the grade of its strongest stress & anxiety benefit. Open one to see each benefit.

StrongModerateWeakNo trials
SupplementMain effects in studiesEvidenceBenefits studied
GABAAnxiety↓ stress†, Sleep/attention↓ anxietyStrong1 of 1
LavenderAnxiety↓ cortisol↓, Sleep/stress↓ 5-10Strong1 of 1
MelatoninAnxiety, cortisol ↓, Sleep, stress ↓Strong1 of 1
TryptophanAnxiety ↑; Trp ↓, Stress hormones ↑; mood ↓Strong1 of 1
St. John's WortDepression ↓, anxiety ↓, Anxiety/somatic ↓Strong1 of 1
Lemon Balm↓ Anxiety/Stress, ↓4‑herb, −1.19 dStrong1 of 1
ChamomileAnxiety ↓ 5.2, Depression/stress ↓Strong1 of 1
TheanineAnxiety, sAA ↓, BP stress response ↓Moderate1 of 1
AshwagandhaStress/anxiety ↓ PSS, Anxiety ↓ HAM-A −41%Moderate1 of 1
SaffronStress/anxiety ↓ p<0.04, Depression/anxiety ↓ p<0.001Moderate1 of 1
Showing 10 of 37 supplements.

What stress & anxiety covers

One benefit that studies measure, and the supplements with the strongest evidence for each.

Stress & Anxiety

Feeling stressed or anxious, and the body's stress response behind it. It is measured on scales such as the Hamilton Anxiety Scale and the State-Trait Anxiety Inventory, and by cortisol in blood or saliva.

37 supplements, 7 strong
  1. GABAStrong, 264
  2. LavenderStrong, 82
  3. MelatoninStrong, 39
  4. TryptophanStrong, 35
  5. St. John's WortStrong, 22