Everyday aches, swelling and body temperature.
Strongest evidence: Electrolytes, Capsaicin and Chondroitin.
Each supplement gets the grade of its strongest daily comfort benefit. Open one to see each benefit.
CapsaicinPain relief, desensitization +30%, Rapid relief, fewer AEsStrong2 of 4
ChondroitinPain/function ↓, NSAID need ↓Strong2 of 4
CaffeinePain relief +26 pp, Faster onset, longer reliefStrong1 of 4
Aloe VeraPain relief: strong, Pain relief: +76%Strong1 of 4
GlucosaminePain/function ↓ ~25-50%, Less NSAID useStrong1 of 4%22%20fill%3D%22%23D9B08C%22%20stroke%3D%22%239A6440%22%2F%3E%3Ccircle%20cx%3D%2229%22%20cy%3D%2215.8%22%20r%3D%223.2%22%20fill%3D%22%23F2871F%22%20stroke%3D%22%23B5560A%22%2F%3E%3C%2Fsvg%3E){kind=small}
TurmericPain ↓; comfort ↑, Function ↑; daily ease ↑Strong1 of 4
Type-II CollagenPain/function improvement, Biomarker shifts -31%Strong1 of 4
RutinVenous swelling ↓, Flight edema 12%→8%Strong1 of 4
BromelainPain ↓, function, Pain ↓, swelling ↓Strong2 of 4
PalmitoylethanolamidePain scores down, Pain/function improvedStrong3 of 4
HMBStrength/mobility +17%, Mass/weight gainsStrong1 of 4
ChamomilePain cut ~50%, Pain relief + symptomsModerate1 of 4
GingerInflammation ↓; swelling relief, Pain/function ↓; swelling reliefModerate1 of 4
LavenderRole QOL +10, No disability changeWeak1 of 4No supplement matches the filter in this list. Clear the filter or choose All.
4 benefits that studies measure, and the supplements with the strongest evidence for each.
General day-to-day physical ease: the absence of the small aches, stiffness and discomforts that are not any single condition. It is measured on broad quality-of-life questionnaires rather than on a specific instrument.
17 supplements, 5 strongCore or skin temperature, and how the body holds it steady under heat, cold or exertion. It is measured directly with a probe, and matters most in studies of exercise in the heat and of fever.
3 supplements, 1 strongReducing pain of any kind. It is measured on a visual analogue scale or a numeric rating scale, and by how much pain medication a person still takes.
32 supplements, 6 strongFluid collecting in tissue, called oedema, usually in the legs, ankles or after an injury. It is measured by limb circumference, by water displacement, and by rated swelling.
14 supplements, 1 strong
