Vitamin C

Does vitamin C help with age-related macular degeneration?

Updated 3 Nov 2026

Short answer

Age-related macular degeneration (AMD) is one of the leading causes of vision loss in older people.[1] The AREDS trial followed 3,640 people aged 55 to 80 with signs of AMD for a mean of 6.3 years.[2] In those who took 500 mg of vitamin C with vitamin E, beta carotene and zinc, the odds of advanced AMD were 28% lower than with placebo.[2] The antioxidants without zinc did not lower the odds significantly.[2] The evidence does not show that vitamin C, alone or with other antioxidants, changes the risk of getting AMD.[1]

Sources (2)

  1. Vitamin C: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. ods.od.nih.gov
  2. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol, 2001. PMID 11594942

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For education; not medical advice. Talk to a doctor before you start, stop or change a supplement.